Paolo Pinton Lab__Signal Transduction

 

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  1. Morciano G, Pedriali G, Sbano L, Iannitti T, Giorgi C, Pinton P (2016) Intersection of mitochondrial fission and fusion machinery with apoptotic pathways: role of Mcl-1. Biol Cell 108:279-293
  2. Bonora M, Morganti C, Morciano G, Pedriali G, Lebiedzinska-Arciszewska M, Aquila G, Giorgi C, Rizzo P, Campo G, Ferrari R, Kroemer G,Wieckowski MR, Galluzzi L, Pinton P (2017) Mitochondrial permeability transition involves dissociation of F1FO ATP synthase dimers and C-ring conformation. EMBO Reports 18(7):1077-89
  3. Pedriali G, Rimessi A, Sbano L, Giorgi C, Wieckowski MR, Previati M, Pinton P (2017) Regulation of ER-mitochondria Ca2+ transfer and its importance for anti-cancer therapies. Front Oncol 7:180
  4. Missiroli S, Patergnani S, Caroccia N, Pedriali G, Perrone M, Previati M, Wieckowski MR, Giorgi C (2018) Mitochondria-associated membranes (MAMs) and inflammation. Cell Death Dis 9(3):329
  5. Morciano G, Preti D, Pedriali G, Aquila G, Missiroli S, Fantinati A, Caroccia N, Pacifico S, Bonora M, Talarico A, Morganti C, Rizzo P, Ferrari R, Wieckowski MR, Campo G, Giorgi C, Trapella C, Pinton P (2018) Discovery of novel 1,3,8-triazaspiro[4.5]decane derivatives that target the c subunit of F1/FO-adenosine triphosphate (ATP) synthase for the treatment of reperfusion damage in myocardial infarction. J Med Chem 61:7131-43
  6. Morciano G, Imamura H, Patergnani S, Pedriali G, Giorgi C, Pinton P (2020) Measurement of ATP concentrations in mitochondria of living cells using luminescence and fluorescence approaches. Methods in Cell Biology 155:199-219
  7. Perrone M, Caroccia N, Genovese I, Missiroli S, Modesti L, Pedriali G, Vezzani B, Vitto VAM, Antenori M, Lebiedzinska-Arciszewska M, Wieckowski MR, Giorgi C, Pinton P (2020) The role of mitochondria-associated membranes in cellular homeostasis and diseases. Int Rev Cell Mol Biol 350:119-196
  8. Rimessi A, Pedriali G, Vezzani B, Tarocco A, Marchi S, Wieckowski MR, Giorgi C, Pinton P (2020) Interorganellar calcium signaling in the regulation of cell metabolism: A cancer perspective. Semin Cell Dev Biol 98:167-180
  9. Morciano G, Patergnani S, Bonora M, Pedriali G, Tarocco A, Bouhamida E, Marchi S, Ancora G, Anania G, Wieckowski MR, Giorgi C, Pinton P (2020) Mitophagy in cardiovascular diseases. J Clin Med 9:892
  10. Bonora M, Patergnani S, Ramaccini D, Morciano G, Pedriali G, Kahsay AE, Bouhamida E, Giorgi C, Wieckowski MR, Pinton P (2020) Physiopathology of the Permeability Transition Pore: Molecular Mechanisms in Human Pathology. Biomolecules 10:998
  11. Pedriali G, Morciano G, Patergnani S, Cimaglia P, Morelli C, Mikus E, Ferrari R, Gasbarro V, Giorgi C, Wieckowski MR, Pinton P (2020) Aortic valve stenosis and mitochondrial dysfunctions: clinical and molecular perspectives. Int J Mol Sci 21(14):4899
  12. Morciano G, Pedriali G, Bonora M, Pavasini R, Mikus E, Calvi S, Bovolenta M, Lebiedzinska-Arciszewska M, Pinotti M, Albertini A, Wieckowski MR, Giorgi C, Ferrari R, Galluzzi L, Campo G, Pinton P (2021) A naturally occurring mutation in ATP synthase subunit c is associated with increased damage following hypoxia/reoxygenation in STEMI patients. Cell Rep 35:108983
  13. Patergnani S, Bonora M, Bouhamida E, Danese A, Marchi S, Morciano G, Previati M, Pedriali G, Rimessi A, Anania G, Giorgi C, Pinton P (2021) Methods to Monitor Mitophagy and Mitochondrial Quality: Implications in Cancer, Neurodegeneration, and Cardiovascular Diseases. Methods Mol Biol 2310:113-159
  14. Morciano G, Patergnani S, Pedriali G, Cimaglia P, Mikus E, Calvi S, Albertini A, Giorgi C, Campo G, Ferrari R, Pinton P (2021) Impairment of mitophagy and autophagy accompanies calcific aortic valve stenosis favoring cell death and the severity of disease. Cardiovascular Research In press
  15. Ramaccini D, Pedriali G, Perrone M, Bouhamida E, Modesti L, Wieckowski MR, Giorgi C, Pinton P, Morciano G. (2022) Some Insights into the Regulation of Cardiac Physiology and Pathology by the Hippo Pathway. Biomedicines 10(3):726
  16. Morciano G, Pedriali G, Mikus E, Cimaglia P, Calvi S, Pavasini R, Albertini A, Ferrari R, Wieckowski MR, Giorgi C, Campo G, Pinton P. (2021) Similarities between fibroblasts and cardiomyocytes in the study of the permeability transition pore. Eur J Clin Invest. e13764
  17. Fantinati A*, Morciano G*, Turrin G, Pedriali G, Pacifico S, Preti D, Albanese V, Illuminati D, Cristofori V, Giorgi C, Tremoli E, Pinton P, Trapella C. (2022) Identification of small-molecule urea derivatives as PTPC modulators targeting the c subunit of F1/Fo-ATP synthase. Bioorg Med Chem Lett 72:128822
  18. Pedriali G, Ramaccini D, Bouhamida E, Wieckowski MR, Giorgi C, Tremoli E, Pinton P. Perspectives on mitochondrial relevance in cardiac ischemia/reperfusion injury. Front Cell Dev Biol. 2022 Dec 6;10:1082095