PhD in Biomedical Sciences and Biotechnology

 

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            1. Rizzo P., Tinello C., Punturieri A., Taniuchi H. A Study of Hydrogen Exchange of Monoclonal Antibodies: Specificity of the Antigen-Binding Induced Conformational Stabilization. Biochimica et Biophysica Acta (1992) 1159, 169-178.
            2. Carbone M., Pass H.I., Rizzo P., Marinetti M., Di Muzio M., Mew D.J.Y., Levine A.S.Procopio A.  Simian Virus 40-like DNA Sequences in Human Pleural Mesothelioma. Oncogene (1994) 9,1781-1790.
            3. Pompetti F., Rizzo P., Simon R.M., Freidlin B., Mew D.J.Y., Pass H.I., Picci P., Levine A.S. and Carbone M.. Oncogene Alterations in Primary, Recurrent and Metastatic Human Bone Tumors. J. Cell. Biochem. (1996) 63, 37-50
            4. Carbone M.,Rizzo P.,Procopio A.,Giuliano M.T., Pass  H.I. ,Gebhardt M.C.,Hansen M.,Malkin D., Bushart G. , Pompetti F., Picci P., Levine A.S., Bergsagel J.D. and Garcea. R.L. SV40-like Sequences in Human Bone Tumors. Oncogene (1996) 13, 527-535
            5. De Luca A., Baldi A., Esposito V., Howard C.M., Bagella L., Rizzo P., Caputi M., Pass H.I.,    Giordano G.G., Baldi F., Carbone M., and Giordano A.  Retinoblastoma Family and Simian Virus-40 Large T antigen in Human Mesotheliomas. Nature Medicine (1997) 3, 913-916
            6. Carbone M, Rizzo P, and Pass HI Simian Virus 40, Poliovaccines and Human Tumors: A Review of Recent Developments. Oncogene (1997) 15:1877-1888 (Review)
            7. Carbone M., Rizzo P., Grimley P.M., Procopio A.Mew D.J.Y., Shridhar V., de Bartolomeis A., Esposito V., Giuliano M.T., Steimberg S.M., Levine A.S., Giordano A. and Pass H.I. Simian Virus-40 Large T antigen binds p53 in Human Mesotheliomas. Nature Medicine (1997) 3, 908-912
            8. Rizzo P., Di Resta I., Powers A., Matker CM., Mutti L., Pass HI. And  Carbone M. The Detection of SV40 in human tumors by PCR. Monaldi Archives for Chest Disease (1998) 53,202-210
            9. Matker CM., Rizzo P., Pass HI., Di Resta I., Powers A., Mutti L., Kast WM., and Carbone M.  The biological activities of simian virus 40 large T antigen and its possible oncogenic effects in humans. Monaldi Archives for Chest Disease (1998) 53, 193-197
            10. Carbone M., Stach R., Di Resta I., Pass HI., and Rizzo P. Simian virus 40 oncogenesis in hamster.  Dev. Biol. Stand. (1998) 94, 273-279
            11. Rizzo P., Di Resta I., Stach R., Pass H.I. and Carbone M. Evidence for and Implications of SV40-like sequences in Human Mesotheliomas and Osteosarcomas. Dev. Biol. Stand. (1998) 94, 33-40
            12. Pass HI., Rizzo P., Donington JS., Wu P., and Carbone Michele. Further validation of SV40-like DNA in human pleural mesotheliomas. Dev. Biol. Stand. (1998) 94, 143-146
            13. Testa JR, Carbone M, Hirvonen A, Khalili K, Krynska B, Linnainmaa K, Pooley FR, Rizzo P, Rusch V, and Xiao GH.  A multi-istitutional study confirms the presence and expression of simian virus 40 in human malignant mesotheliomas. Cancer Research (Advances in Brief) (1998) 58: 4505-4509
            14. Pass HI, Donington JS, Wu P, Rizzo P, Nishimura M, Kennedy R, and Carbone M.  Human mesotheliomas contain the simian virus 40 (SV40) regulatory region and large (T) antigen DNA sequences. J. Thoracic and Cardiovascular Surgery (1998) 116: 854-859
            15. Rizzo P., Tinello C., Pearlstein R.A., Taniuchi H.  Antibody Immunodiversity: A study on the Marked Specificity Difference Between Two Anti-Yeast Iso-1 Cytochrome c Monoclonal Antibodies Whose Epitopes Are Closely Related. Journal of Protein Chemistry (1999), 18 (5) 523-532
            16. Carbone M, Fisher S, Powers A, Pass HI, Rizzo P. New molecular and epidemiological issues in mesothelioma: role of SV40. J Cell Physiol. 1999 Aug;180(2):167-72 (Review)
            17. Rizzo P, Di Resta I, Powers A, Ratner H, and Carbone M. Unique strains of SV40 in commercial poliovaccines from 1955 not readily identifiable with current testing for SV40 infection.  Cancer Research (Advances in Brief) (1999) 59:6103-6105
            18. Rizzo P, Carbone M, Fisher S, Matker C, Swinnen LJ, Powers A, Di Resta I, Alkan S, Pass HI, and Fisher RI. SV40 is present in most US human mesotheliomas but it is rarely present in non –Hodgkin’s lymphoma. Chest. 1999 Dec;116(6 Suppl):470S-473S
            19. Xiao SY, Rizzo P, and Carbone M. Benign papillary mesothelioma of tunica vaginalis testis.  Arch.Path.Lab.Med. 2000 Jan 124(1):143-7.
            20. Carbone M, Rizzo P, Pass HI Simian virus 40: the link with human malignant mesothelioma is well established. Anticancer Res. 2000 Mar-Apr;20(2A):875-7. (Review)
            21. Bocchetta M, Di Resta I, Powers A, Fresco I, Tosolini A, Testa JR, Pass HI, Rizzo P and Carbone M  Human mesothelial cells are unusually susceptible to simian virus 40-mediated transformation and asbestos cocarcinogenicity. Proc Natl Acad Sci USA. 2000 Aug 29;97(18):10214-9.
            22. Rizzo P, Matker C, Setlak P, Heeney JL, Powers A, Ratner H and Carbone M. No evidence of HIV and SIV sequences in two separate lots of poliovaccines used in the first poliovaccine campaign in the US. Virology. 2001 Aug 15;287(1):13-7
            23. Rizzo P, Bocchetta M, Powers A, Foddis R, Stekala E, Pass HI, Carbone M. SV40 and the pathogenesis of mesothelioma. Semin Cancer Biol. 2001 Feb; 11(1):63-71.(Review)
            24. Foddis R, De Rienzo A Broccoli D, Bocchetta M, Stekala E, Rizzo P, Tosolini A, Grobelny JV, Jhanwar SC, Pass HI, Testa JR, Carbone M.. SV40 infection induces telomerases activity in human mesothelial cells. Oncogene 2002 Feb 21;21(9):1434-42
            25. Weijzen S, Rizzo P, Braid M, Vaishnav R, Jonkheer SM, Zlobin A, Osborne BA, Gottipati S, Aster JC, Hahn WC, Rudolf M, Siziopikou K, Kast WM, Miele L Activation of Notch-1 signaling maintains the neoplastic phenotype in human Ras-transformed cells. Nat Med. 2002 Aug 19
            26. Carbone M, Rizzo P, Powers A, Bocchetta M, Fresco R, Krausz T.  Molecular analyses, morphology and immunohistochemistry together differentiate pleural synovial sarcomas from mesotheliomas: clinical implications. Anticancer Res. 2002 Nov-Dec; 22(6B):3443-8.
            27. Carbone M, Bocchetta M, Cristaudo A, Emri S, Gazdar A, Jasani B, Lednicky J,Miele L, Mutti L, Pass HI, Ramael M, Rizzo P, Testa JR, Weggen S, Yeung A. SV40 and human brain tumors. Int J Cancer. 2003 Aug 10; 106(1):140-2; author reply 143-5.
            28. Qin JZ, Ziffra J, Stennet L, Bodner B, Bonish BK, Chaturvedi V, Bennet F, Pollock PM, Trent JM, Hendrix MJ, Rizzo P, MieleL, Nickoloff BJ. Proteasome inhibitors trigger NOXA-mediated apoptosis in melanoma and myeloma cells. Cancer Res. 2005 Jul 15;65(14):6282-93.
            29. Cutrone R, Lednicky J, Dunn G, Rizzo P, Bocchetta M, Chumakov K, Minor P and Carbone M. Some poliovaccines were contaminated with infectious SV40 after 1961. Cancer Res. 2005 Nov 15;65(22):10273-9.
            30. Rizzo P., Miao H., D’Souza G., Osipo C., Yun J., Whitehouse L., Zhao H., Mascarenhas J, Wyatt D, Antico G, Hao L, Yao K, Rajan P, Hicks C, Siziopikou K, Selvaggi S, Koerner F, Bashir A, Lendahl U , Chaturvedi U, Qin JZ, Tonetti D, Albain K, Nickoloff B and Miele L Cross-Talk Between Notch And The Estrogen Receptor In Breast Cancer Suggests New Therapeutic Approaches. Cancer Res. 2008 Jul 1;68(13):5226-35.
            31. Osipo C, Patel P, Rizzo P , Clementz A, Hao L, Golde T, and Miele L. ErbB-2 Inhibition Activates Notch-1 and Sensitizes Breast Cancer Cells to a Gamma-Secretase Inhibitor. Oncogene. 2008 May 12 (Epub ahead of print.)
            32. Song L., Peng Y, Pannuti  A., Rizzo P., Chaturvedi V, Weijzen S , Kast WM,  Stone PJB, Santos L., Loredo A., Lendhal U, Sonenshein G, Qin JZ, Nickoloff BJ and Miele L Notch -1 associate with IKKα and regulates IKK activity in cervical cancer cells Oncogene. 2008 Jun 16
            33. Rizzo P, Osipo C., Foreman K Golde T, Osborne B, Miele L, Rational targeting of Notch signaling in cancer Oncogene. 2008 Sep 1;27(38):51 (Review)
            34. Hao L., Rizzo P., Osipo C., Pannuti, Cheung L., Sonenshein G., Osborne B., Miele L. Notch-1 activates estrogen receptor alpha –mediated  trascription  via IKK alpha in the absence of estradiol. Oncogene 2009 Jan 14; 29(2): 201-213
            35. Yao K, Rizzo P., Rajan P., Albain KS, Rychlik K., Sha S., Miele L. Notch -1 and 4 receptors as prognostic markers in breast cancer. Int. J Surg Pathol 2010, May 5
            36. Pannuti A., Foreman K., Rizzo P., Osipo C., Golde T., Osborne B., Miele L Targeting Cancer Stem Cells through Notch Signaling Clinical Cancer Research 2010 16(12):3141-52) (Review)
            37. Ceconi C, Guardigli G, Rizzo P, Francolini G and Ferrari R Heart Rate Lowering in Coronary Artery Disease Management Introduction: the heart rate story European Heart Journal Supplements (2011) 13 (Supplement C), C4–C13 (Review)
            38. Rizzo P, Miele L and Ferrari R The Notch Pathway: a crossroad between the life and death of the endothelium ( Eur Heart J. 2012 May 29. [Epub ahead of print]) (Review)
            39. Gu JW, Rizzo P, Pannuti A; Golde T, Osborne B, Miele L Notch Signals In The Endothelium And Cancer "Stem-like" Cells: Opportunities For Cancer Therapy (Vasc Cell. 2012 Apr 9;4:7.) (Review) (cit. 11)
            40. Caliceti C, Aquila G, Pannella M, Morelli MB, Fortini C, Pinton P, Bonora M, Hrelia S, Pannuti A, Miele L, Rizzo P and Ferrari R 17b-Estradiol Enhances Signalling Mediated by VEGF-A-Delta like ligand 4-Notch1 axis in Human Endothelial Cells. Plos One (2013) Aug 13:8 (8) e71440 (corresponding author)
            41. Yun J, Pannuti A, Espinoza I, Zhu H, Hicks C, Zhu X, Caskey M, Rizzo P, D'Souza G, Backus K, Denning MF, Coon J, Sun M, Bresnick EH, Osipo C, Wu J, Strack PR, Tonetti DA, Miele L.Crosstalk between PKCα and Notch-4 in endocrine-resistant breast cancer cells. Oncogenesis. 2013 Aug 5;2,e60 (cit. 1)
            42. Aquila G, Pannella M, Morelli MB, Caliceti C, Fortini C, Rizzo P and Ferrari R The role of Notch pathway in cardiovascular diseases, Glob Cardiol Sci Pract. 2013 Dec 30;2013(4):364-71 (Review)
            43. Rizzo P and Mele D What is the role of the Notch pathway in cancer-induced cardiotoxicity. Dialogs in Cardiovascular Medicine 2013, 18,1 (Review)
            44. Caliceti C, Nigro P, Rizzo P and Ferrari R. ROS, Notch and Wnt signaling pathways: cross-talk between three major regulators of cardiovascular biology, Biomed Res Int. 2014;2014:318714. Epub 2014 Feb 4. (Review)
            45. Voltan R, Zauli G, Rizzo P, Fucili A, Pannella M, Marci R, Tisato V, Ferrari R, Secchiero P.In vitro endothelial cell proliferation assay reveals distinct levels of proangiogenic cytokines characterizing sera of healthy subjects and of patients with heart failure. Mediators Inflamm. 2014;2014. Epub 2014 Mar 23
            46. Fortini C, Cesselli D, , Beltrami AP, Bergamin N, Caragnano A, Moretti L, Cecaro F, Aquila G, Rizzo P, Riberti C, Tavazzi L, Fucili A, Beltrami CA, Ferrari R. Alteration of Notch signaling and functionality of adipose tissue derived mesenchymal stem cells in heart failure. Int J Cardiol. 2014 Jun 1;174(1):119-26. Epub 2014 Apr 8.
            47. Ferrari R and Rizzo P The Notch pathway: a novel target for myocardial remodelling therapy? Eur Heart J. 2014 Aug 21;35(32):2140-2145. Epub 2014 Jun 26 (Review)
            48. Mele D, Rizzo P, Pollina AV, Fiorencis A, Ferrari R .Cancer Therapy-Induced Cardiotoxicity: Role of Ultrasound Deformation Imaging as an Aid to Early Diagnosis. Ultrasound Med Biol. 2015 Jan 22. pii: S0301-5629(14)00762-5. doi: 10.1016/j.ultrasmedbio.2014.11.015.(Review) Epub ahead of print
            49. Caliceti C, Rizzo P, Cicero AF. Potential Benefits of Berberine in the Management of Perimenopausal Syndrome. Oxid Med Cell Longev. 2015;2015:723093. Epub 2015 Feb 17. Review.
            50. Rizzo P and Ferrari R. The Notch pathway: a new therapeutic target in atherosclerosis? Eur Heart J Suppl 2015 17: A74-A76 (Review)
            51. Caliceti C, Rizzo P, Cicero AF. Potential benefits of berberine in the management of perimenopausal syndrome. Oxid Med Cell Longev.. Epub 2015 Feb 17. Review.
            52. Rizzo P, Mele D, Caliceti C, Fortini C, Clementz AC, Morelli MB, Aquila G, Ameri G and Ferrari R. The Role of Notch in the Cardiovascular System: Potential Adverse Effects of Investigational Notch Inhibitors (Review) Front Oncol. 2015 Jan 13;4:384.
            53. Yun J, Espinoza I, Pannuti A, Romero D, Martinez L, Caskey M, Stanculescu A, Bocchetta M, Rizzo P, Band V, Band H, Kim HM, Park SK, Kang KW, Avantaggiati ML, Gomez CR, Golde T, Osborne B, Miele L. p53 Modulates Notch Signaling in MCF-7 Breast Cancer Cells by Associating With the Notch Transcriptional Complex Via MAML1. J Cell Physiol. 2015 Dec;230(12):3115-27. doi: 10.1002/jcp.25052.
            54. Pannella M, Caliceti C, Fortini F, Aquila G, Vieceli Dalla Sega F, Pannuti A, Fortini C, Morelli MB, Fucili A, Francolini G, Voltan R, Secchiero P, Dinelli G, Leoncini E, Ferracin M, Hrelia S, Miele L, Rizzo P. Serum from Advanced Heart Failure Patients Promotes Angiogenic Sprouting and Affects the Notch Pathway in Human Endothelial Cells. J Cell Physiol. 2016 Mar 14. doi: 10.1002/jcp.25373. [Epub ahead of prin t(corresponding author)
            55. Clementz AG, Rizzo P, Martini P, Tognon M Roles of dysregulated Notch pathway and small DNA tumor viruses in cancer initiation and progression Journal of Cancer Metastasis and Treatment 2016
            56. Ongaro A, Pellati A, Bagheri L, Rizzo P, Caliceti C, Massari L, DeMattei M. Characterization of Notch Signaling During Osteogenic Differentiation in Human Osteosarcoma Cell Line MG63. J Cell Physiol. 2016 Mar 4.
            57. Campo G, Morciano G, Pavasini R, Bonora M, Sbano L, Biscaglia S, Bovolenta M, Pinotti M, Punzetti S, Rizzo P, Aquila G, Giorgi C, Ferrari R, Pinton P. Fo ATP synthase C subunit serum levels in patients with ST-segment Elevation Myocardial Infarction: Preliminary findings. Int J Cardiol. 2016 Oct 15;221:993-7.
            58. Ferrari R, Malagù M, Biscaglia S, Fucili A, Rizzo P. Remodelling after an Infarct: Crosstalk between Life and Death. Cardiology. 2016;135(2):68-76.
            59. Mercurio V, Pirozzi F, Lazzarini E, Marone G,  Rizzo P, Agnetti G, Tocchetti CG, Ghigo A, Ameri P Models of Heart Failure Based on the Cardiotoxicity of Anticancer Drugs J Card Fail. 2016 Jun;22(6):449-58
            60. Campo G, Vieceli Dalla Sega F, Pavasini R, Aquila G, Gallo F, Fortini F, Tonet E, Cimaglia P, Del Franco A, Pestelli G, Contoli M,. Balla C, Biscaglia S, Rizzo P, Ferrari R. Biological Effects of Ticagrelor over Clopidogrel in Patients with Stable Coronary Artery Disease and Chronic Obstructive Pulmonary Disease. Thromb Haemost. 2017 Mar 23. doi: 10.1160/TH16-12-0973. [Epub ahead of print]
            61. Vieceli Dalla Sega F, Aquila G, Fortini F,  Vaccarezza M, Secchiero P, Rizzo P, Campo G Context-dependent function of ROS in the vascular endothelium: the role of the Notch pathway and Shear Stress  Biofactors. 2017 Apr 17. doi: 10.1002/biof.1359. [Epub ahead of print] (corresponding author)
            62. Aquila G,  Fortini C, Pannuti A, Delbue S, Pannella M, Morelli MB, Caliceti C, Castriota F, De Mattei M, Ongaro A,  Pellati A, Ferrante P, Miele L, Tavazzi L, Ferrari R, Rizzo P and. Cremonesi A. Distinct gene expression profiles associated with Notch ligands Delta-like 4 and Jagged1 in plaque material from peripheral artery disease patients Journal of Translational Medicine- 2017 May 4;15(1):98. doi: 10.1186/s12967-017-1199-3. (corresponding author)
            63. Caliceti C, Rizzo P, Ferrari R, Fortini F, Aquila G,  Leoncini E,  Zambonin L,  Rizzo B, Calabria D,  Mirasoli M, Guardigli, Hrelia S,  Roda A, Cicero A. Novel role of the nutraceutical bioactive compound Berberine in lectin-like OxLDL receptor 1 -mediated endothelial dysfunction in comparison to Lovastatin. Nutrition, Metabolism & Cardiovascular Diseases-2017 Apr 19. pii: S0939-4753(17)30065-0. doi: 10.1016/j.numecd.2017.04.002
            64. Bonora M, Morganti C,  Morciano G,  Pedriali G, Lebiedzinska M, Aquila G, Giorgi C, Rizzo P, Campo G, Ferrari R, Kroemer G, Wieckowski RM, Galluzzi L, Pinton P. Mitochondrial permeability transition involves dissociation of F1FO ATP synthase dimers and correct C-ring conformation- EMBO Reports- In Press
            65. Bagheri L, Pellati A, Rizzo P, Aquila G, Massari L, De Mattei M, Ongaro A. Notch pathway is active during osteogenic differentiation of human bone marrow mesenchymal stem cells induced by pulsed electromagnetic fields. J Tissue Eng Regen Med. 2017 May 8. doi: 10.1002/term.2455
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