PhD in Biomedical Sciences and Biotechnology
Home – PhD students – Faculty – Seminars
- Breveglieri G, Travan A, D'Aversa E, Cosenza LC, Pellegatti P, Guerra G, Gambari R, Borgatti M. Postnatal and non-invasive prenatal detection of β-thalassemia mutations based on Taqman genotyping assays. PLoS One. 2017 Feb 24;12(2):e0172756. doi: 10.1371/journal.pone.0172756. eCollection 2017. PubMed PMID: 28235086; PubMed Central PMCID: PMC5325530.
- Montagner G, Bezzerri V, Cabrini G, Fabbri E, Borgatti M, Lampronti I, Finotti A, Nielsen PE, Gambari R. An antisense peptide nucleic acid against Pseudomonas aeruginosa inhibiting bacterial-induced inflammatory responses in the cystic fibrosis IB3-1 cellular model system. Int J Biol Macromol. 2017 Jun;99:492-498. doi: 10.1016/j.ijbiomac.2017.02.011. Epub 2017 Feb 3. PubMed PMID: 28167114.
- Finotti A, Borgatti M, Gambari R. Ground state naïve pluripotent stem cells and CRISPR/Cas9 gene correction for β-thalassemia. Stem Cell Investig. 2016 Oct 25;3:66. eCollection 2016. PubMed PMID: 27868048; PubMed Central PMCID: PMC5104583.
- Breveglieri G, Gallo TE, Travan A, Pellegatti P, Guerra G, Gambari R, Borgatti M. Surface plasmon resonance analysis to detect the β (+)IVSI-110 thalassemia mutation in circulating cell-free fetal DNA. Clin Chim Acta. 2016 Nov 1;462:133-134. doi: 10.1016/j.cca.2016.09.008. PubMed PMID: 27642085.
- Cosenza LC, Breda L, Breveglieri G, Zuccato C, Finotti A, Lampronti I, Borgatti M, Chiavilli F, Gamberini MR, Satta S, Manunza L, De Martis FR, Moi P, Rivella S, Gambari R, Bianchi N. A validated cellular biobank for β - thalassemia. J Transl Med. 2016 Sep 2;14:255. doi: 10.1186/s12967-016-1016-4. PubMed PMID: 27590532; PubMed Central PMCID: PMC5010737.
- Altamura E, Borgatti M, Finotti A, Gasparello J, Gambari R, Spinelli M, Castaldo R, Altamura N. Chemical-Induced Read-Through at Premature Termination Codons Determined by a Rapid Dual-Fluorescence System Based on S. cerevisiae. PLoS One. 2016 Apr 27;11(4):e0154260. doi: 10.1371/journal.pone.0154260. PubMed PMID: 27119736; PubMed Central PMCID: PMC4847774.
- Fabbri E, Montagner G, Bianchi N, Finotti A, Borgatti M, Lampronti I, Cabrini G, Gambari R. MicroRNA miR-93-5p regulates expression of IL-8 and VEGF in neuroblastoma SK-N-AS cells. Oncol Rep. 2016 May;35(5):2866-72. doi: 10.3892/or.2016.4676. PubMed PMID: 26986724.
- Bianchi N, Cosenza LC, Lampronti I, Finotti A, Breveglieri G, Zuccato C, Fabbri E, Marzaro G, Chilin A, De Angelis G, Borgatti M, Gallucci C, Alfieri C, Ribersani M, Isgrò A, Marziali M, Gaziev J, Morrone A, Sodani P, Lucarelli G, Gambari R, Paciaroni K. Structural and Functional Insights on an Uncharacterized Aγ -Globin-Gene Polymorphism Present in Four β 0-Thalassemia Families with High Fetal Hemoglobin Levels. Mol Diagn Ther. 2016 Apr;20(2):161-73. doi: 10.1007/s40291-016-0187-2. PubMed PMID: 26897028.
- Breveglieri G, Bassi E, Carlassara S, Cosenza LC, Pellegatti P, Guerra G, Finotti A, Gambari R, Borgatti M. Y-chromosome identification in circulating cell-free fetal DNA using surface plasmon resonance. Prenat Diagn. 2016 Apr;36(4):353-61. doi: 10.1002/pd.4788. PubMed PMID: 26850691.
- Brognara E, Fabbri E, Montagner G, Gasparello J, Manicardi A, Corradini R, Bianchi N, Finotti A, Breveglieri G, Borgatti M, Lampronti I, Milani R, Dechecchi MC, Cabrini G, Gambari R. High levels of apoptosis are induced in human glioma cell lines by co-administration of peptide nucleic acids targeting miR-221 and miR-222. Int J Oncol. 2016 Mar;48(3):1029-38. doi: 10.3892/ijo.2015.3308. PubMed PMID: 26708164.
- Fabbri E, Brognara E, Montagner G, Ghimenton C, Eccher A, Cantù C,Khalil S, Bezzerri V, Provezza L, Bianchi N, Finotti A, Borgatti M, Moretto G, Chilosi M, Cabrini G, Gambari R. Regulation of IL-8 gene expression in gliomas by microRNA miR-93. BMC Cancer. 2015 Oct 8;15:661. doi: 10.1186/s12885-015-1659-1. PubMed PMID: 26449498; PubMed Central PMCID: PMC4598972.
- Breveglieri G, Finotti A, Borgatti M, Gambari R. Recent patents and technology transfer for molecular diagnosis of β -thalassemia and other hemoglobinopathies. Expert Opin Ther Pat. 2015;25(12):1453-76. doi: 10.1517/13543776.2015.1090427. Review. PubMed PMID: 26413795.
- Finotti A, Gasparello J, Breveglieri G, Cosenza LC, Montagner G, Bresciani A, Altamura S, Bianchi N, Martini E, Gallerani E, Borgatti M, Gambari R. Development and characterization of K562 cell clones expressing BCL11A-XL: Decreased hemoglobin production with fetal hemoglobin inducers and its rescue with mithramycin. Exp Hematol. 2015 Dec;43(12):1062-1071.e3. doi: 10.1016/j.exphem.2015.08.011. PubMed PMID: 26342260; PubMed Central PMCID: PMC4670904.
- Breveglieri G, Mancini I, Bianchi N, Lampronti I, Salvatori F, Fabbri E, Zuccato C, Cosenza LC, Montagner G, Borgatti M, Altruda F, Fagoonee S, Carandina G, Rubini M, Aiello V, Breda L, Rivella S, Gambari R, Finotti A. Generation and Characterization of a Transgenic Mouse Carrying a Functional Human β-Globin Gene with the IVSI-6 Thalassemia Mutation. Biomed Res Int. 2015;2015:687635. doi: 10.1155/2015/687635. PubMed PMID: 26097845; PubMed Central PMCID: PMC4434229.
- Marzaro G, Lampronti I, Borgatti M, Manzini P, Gambari R, Chilin A. Psoralen derivatives as inhibitors of NF-κ B interaction: the critical role of the furan ring. Mol Divers. 2015 Aug;19(3):551-61. doi: 10.1007/s11030-015-9586-2. PubMed PMID: 25869956.
- Bianchi N, Finotti A, Ferracin M, Lampronti I, Zuccato C, Breveglieri G, Brognara E, Fabbri E, Borgatti M, Negrini M, Gambari R. Increase of microRNA-210, decrease of raptor gene expression and alteration of mammalian target of rapamycin regulated proteins following mithramycin treatment of human erythroid cells. PLoS One. 2015 Apr 7;10(4):e0121567. doi: 10.1371/journal.pone. 0121567. PubMed PMID: 25849663; PubMed Central PMCID: PMC4388523.
- Muresan XM, Cervellati F, Sticozzi C, Belmonte G, Chui CH, Lampronti I, Borgatti M, Gambari R, Valacchi G. The loss of cellular junctions in epithelial lung cells induced by cigarette smoke is attenuated by corilagin. Oxid Med Cell Longev. 2015;2015:631758. doi: 10.1155/2015/631758. PubMed PMID: 25802682; PubMed Central PMCID: PMC4354730.
- Bianchi N, Chiarabelli C, Zuccato C, Lampronti I, Borgatti M, Amari G, Delcanale M, Chiavilli F, Prus E, Fibach E, Gambari R. Erythroid differentiation ability of butyric acid analogues: identification of basal chemical structures of new inducers of foetal haemoglobin. Eur J Pharmacol. 2015 Apr 5;752:84-91. doi: 10.1016/j.ejphar.2015.02.018. PubMed PMID: 25701725.
- Finotti A, Bianchi N, Fabbri E, Borgatti M, Breveglieri G, Gasparello J, Gambari R. Erythroid induction of K562 cells treated with mithramycin is associated with inhibition of raptor gene transcription and mammalian target of rapamycin complex 1 (mTORC1) functions. Pharmacol Res. 2015 Jan;91:57-68. doi: 10.1016/j.phrs.2014.11.005. PubMed PMID: 25478892; PubMed Central PMCID: PMC4309890.
- Montagner G, Gemmo C, Fabbri E, Manicardi A, Accardo I, Bianchi N, Finotti A, Breveglieri G, Salvatori F, Borgatti M, Lampronti I, Bresciani A, Altamura S, Corradini R, Gambari R. Peptide nucleic acids targeting β -globin mRNAs selectively inhibit hemoglobin production in murine erythroleukemia cells. Int J Mol Med. 2015 Jan;35(1):51-8. doi: 10.3892/ijmm.2014.2005. PubMed PMID: 25405921; PubMed Central PMCID: PMC4249754.
- Bezzerri V, Avitabile C, Dechecchi MC, Lampronti I, Borgatti M, Montagner G, Cabrini G, Gambari R, Romanelli A. Antibacterial and anti-inflammatory activity of a temporin B peptide analogue on an in vitro model of cystic fibrosis. J Pept Sci. 2014 Oct;20(10):822-30. doi: 10.1002/psc.2674. PubMed PMID: 25201563.
- Brognara E, Fabbri E, Bazzoli E, Montagner G, Ghimenton C, Eccher A, Cantù C, Manicardi A, Bianchi N, Finotti A, Breveglieri G, Borgatti M, Corradini R, Bezzerri V, Cabrini G, Gambari R. Uptake by human glioma cell lines and biological effects of a peptide-nucleic acids targeting miR-221. J Neurooncol. 2014 May;118(1):19-28. doi: 10.1007/s11060-014-1405-6. PubMed PMID: 24595467.
- Fabbri E, Borgatti M, Montagner G, Bianchi N, Finotti A, Lampronti I, Bezzerri V, Dechecchi MC, Cabrini G, Gambari R. Expression of microRNA-93 and Interleukin-8 during Pseudomonas aeruginosa-mediated induction of proinflammatory responses. Am J Respir Cell Mol Biol. 2014 Jun;50(6):1144-55. doi: 10.1165/rcmb.2013-0160OC. PubMed PMID: 24433094.
- Guerrini A, Mancini I, Maietti S, Rossi D, Poli F, Sacchetti G, Gambari R, Borgatti M. Expression of pro-inflammatory interleukin-8 is reduced by ayurvedic decoctions. Phytother Res. 2014 Aug;28(8):1173-81. doi: 10.1002/ptr.5109. PubMed PMID: 24395450.
- De Vito P, Incerpi S, Affabris E, Percario Z, Borgatti M, Gambari R, Pedersen JZ, Luly P. Effect of atrial natriuretic peptide on reactive oxygen species-induced by hydrogen peroxide in THP-1 monocytes: role in cell growth, migration and cytokine release. Peptides. 2013 Dec;50:100-8. doi: 10.1016/j.peptides.2013.09.002. PubMed PMID: 24120989.
- Abonnenc M, Borgatti M, Fabbri E, Gavioli R, Fortini C, Destro F, Altomare L, Manaresi N, Medoro G, Romani A, Tartagni M, Lo Monaco E, Giacomini P, Guerrieri R, Gambari R. Lysis-on-chip of single target cells following forced interaction with CTLs or NK cells on a dielectrophoresis-based array. J Immunol. 2013 Oct 1;191(7):3545-52. doi: 10.4049/jimmunol.1300890. PubMed PMID: 24006464.
- Abonnenc M, Manaresi N, Borgatti M, Medoro G, Fabbri E, Romani A, Altomare L, Tartagni M, Rizzo R, Baricordi O, Tremante E, Lo Monaco E, Giacomini P, Guerrieri R, Gambari R. Programmable interactions of functionalized single bioparticles in a dielectrophoresis-based microarray chip. Anal Chem. 2013 Sep 3;85(17): 8219-24. doi: 10.1021/ac401296m. PubMed PMID: 23968491.
- Lampronti I, Borgatti M, Vertuani S, Manfredini S, Gambari R. Modulation of the expression of the proinflammatory IL-8 gene in cystic fibrosis cells by extracts deriving from olive mill waste water. Evid Based Complement Alternat Med. 2013;2013:960603. doi: 10.1155/2013/960603. PubMed PMID: 23935691; PubMed Central PMCID: PMC3723063.
- Saab AM, Dobmeier M, Koenig B, Fabri E, Finotti A, Borgatti M, Lampronti I, Bernardi F, Efferth T, Gambari R. Antiproliferative and erythroid differentiation of piperazine and triphenyl derivatives against k-562 human chronic myelogenous leukemia. Anticancer Res. 2013 Aug;33(8):3027-32. PubMed PMID: 23898056.
- Altamura N, Castaldo R, Finotti A, Breveglieri G, Salvatori F, Zuccato C, Gambari R, Panin GC, Borgatti M. Tobramycin is a suppressor of premature termination codons. J Cyst Fibros. 2013 Dec;12(6):806-11. doi: 10.1016/j.jcf.2013.02.007. PubMed PMID: 23540394.
- Marzaro G, Guiotto A, Borgatti M, Finotti A, Gambari R, Breveglieri G, Chilin A. Psoralen derivatives as inhibitors of NF-κ B/DNA interaction: synthesis, molecular modeling, 3D-QSAR, and biological evaluation. J Med Chem. 2013 Mar 14;56(5):1830-42. doi: 10.1021/jm3009647. PubMed PMID: 23414143.
- Rossi D, Guerrini A, Bruni R, Brognara E, Borgatti M, Gambari R, Maietti S, Sacchetti G. trans-Resveratrol in nutraceuticals: issues in retail quality and effectiveness. Molecules. 2012 Oct 22;17(10):12393-405. doi: 10.3390/molecules171012393. PubMed PMID: 23090020.
- Khan MT, Dedachi K, Matsui T, Kurita N, Borgatti M, Gambari R, Sylte I. Dipeptide inhibitors of thermolysin and angiotensin I-converting enzyme. Curr Top Med Chem. 2012;12(16):1748-62. PubMed PMID: 23030610.
- Brognara E, Fabbri E, Aimi F, Manicardi A, Bianchi N, Finotti A, Breveglieri G, Borgatti M, Corradini R, Marchelli R, Gambari R. Peptide nucleic acids targeting miR-221 modulate p27Kip1 expression in breast cancer MDA-MB-231 cells. Int J Oncol. 2012 Dec;41(6):2119-27. doi: 10.3892/ijo.2012.1632. PubMed PMID: 22992757.
- Finotti A, Borgatti M, Bezzerri V, Nicolis E, Lampronti I, Dechecchi M, Mancini I, Cabrini G, Saviano M, Avitabile C, Romanelli A, Gambari R. Effects of decoy molecules targeting NF-kappaB transcription factors in Cystic fibrosis IB3-1 cells: recruitment of NF-kappaB to the IL-8 gene promoter and transcription of the IL-8 gene. Artif DNA PNA XNA. 2012 Apr-Jun;3(2):97-296. doi: 10.4161/adna.21061. PubMed PMID: 22772035; PubMed Central PMCID: PMC3429536.
- Gambari R, Borgatti M, Lampronti I, Fabbri E, Brognara E, Bianchi N, Piccagli L, Yuen MC, Kan CW, Hau DK, Fong WF, Wong WY, Wong RS, Chui CH. Corilagin is a potent inhibitor of NF-kappaB activity and downregulates TNF-alpha induced expression of IL-8 gene in cystic fibrosis IB3-1 cells. Int Immunopharmacol. 2012 Jul;13(3):308-15. doi: 10.1016/j.intimp.2012.04.010. PubMed PMID: 22561123.
- Zuccato C, Breda L, Salvatori F, Breveglieri G, Gardenghi S, Bianchi N, Brognara E, Lampronti I, Borgatti M, Rivella S, Gambari R. A combined approach for β -thalassemia based on gene therapy-mediated adult hemoglobin (HbA) production and fetal hemoglobin (HbF) induction. Ann Hematol. 2012 Aug;91(8):1201-13. doi: 10.1007/s00277-012-1430-5. PubMed PMID: 22460946; PubMed Central PMCID: PMC3389244.
- Fibach E, Prus E, Bianchi N, Zuccato C, Breveglieri G, Salvatori F, Finotti A, Lipucci di Paola M, Brognara E, Lampronti I, Borgatti M, Gambari R. Resveratrol: Antioxidant activity and induction of fetal hemoglobin in erythroid cells from normal donors and β -thalassemia patients. Int J Mol Med. 2012 Jun;29(6):974-82. doi: 10.3892/ijmm.2012.928. PubMed PMID: 22378234.
- Khan MT, Mischiati C, Ather A, Ohyama T, Dedachi K, Borgatti M, Kurita N, Gambari R. Structure-based analysis of the molecular recognitions between HIV-1 TAR-RNA and transcription factor nuclear factor-kappaB (NFkB). Curr Top Med Chem. 2012;12(8):814-27. Review. PubMed PMID: 22352910.
- Bianchi N, Zuccato C, Finotti A, Lampronti I, Borgatti M, Gambari R. Involvement of miRNA in erythroid differentiation. Epigenomics. 2012 Feb;4(1):51-65. doi: 10.2217/epi.11.104. Review. PubMed PMID: 22332658.
- Saab AM, Lampronti I, Borgatti M, Finotti A, Harb F, Safi S, Gambari R. In vitro evaluation of the anti-proliferative activities of the wood essential oils of three Cedrus species against K562 human chronic myelogenous leukaemia cells. Nat Prod Res. 2012;26(23):2227-31. doi: 10.1080/14786419.2011.643885. PubMed PMID: 22168262.
- Fabbri E, Brognara E, Borgatti M, Lampronti I, Finotti A, Bianchi N, Sforza S, Tedeschi T, Manicardi A, Marchelli R, Corradini R, Gambari R. miRNA therapeutics: delivery and biological activity of peptide nucleic acids targeting miRNAs. Epigenomics. 2011 Dec;3(6):733-45. doi: 10.2217/epi.11.90. Review. PubMed PMID: 22126292.
- Bezzerri V, Borgatti M, Finotti A, Tamanini A, Gambari R, Cabrini G. Mapping the transcriptional machinery of the IL-8 gene in human bronchial epithelial cells. J Immunol. 2011 Dec 1;187(11):6069-81. doi: 10.4049/jimmunol. 1100821. PubMed PMID: 22031759.
- Saab AM, Tundis R, Loizzo MR, Lampronti I, Borgatti M, Gambari R, Menichini F, Esseily F, Menichini F. Antioxidant and antiproliferative activity of Laurus nobilis L. (Lauraceae) leaves and seeds essential oils against K562 human chronic myelogenous leukaemia cells. Nat Prod Res. 2012;26(18):1741-5. doi: 10.1080/14786419.2011.608674. PubMed PMID: 22017546.
- Fabbri E, Manicardi A, Tedeschi T, Sforza S, Bianchi N, Brognara E, Finotti A, Breveglieri G, Borgatti M, Corradini R, Marchelli R, Gambari R. Modulation of the biological activity of microRNA-210 with peptide nucleic acids (PNAs). ChemMedChem. 2011 Dec 9;6(12):2192-202. doi: 10.1002/cmdc.201100270. PubMed PMID: 22012891.
- D'Agata R, Breveglieri G, Zanoli LM, Borgatti M, Spoto G, Gambari R. Direct detection of point mutations in nonamplified human genomic DNA. Anal Chem. 2011 Nov 15;83(22):8711-7. doi: 10.1021/ac2021932. PubMed PMID: 21978174.
- Brognara E, Lampronti I, Breveglieri G, Accetta A, Corradini R, Manicardi A, Borgatti M, Canella A, Multineddu C, Marchelli R, Gambari R. C(5) modified uracil derivatives showing antiproliferative and erythroid differentiation inducing activities on human chronic myelogenous leukemia K562 cells. Eur J Pharmacol. 2011 Dec 15;672(1-3):30-7. doi: 10.1016/j.ejphar.2011.09.024. PubMed PMID: 21958870; PubMed Central PMCID: PMC3271358.
- Borgatti M, Chilin A, Piccagli L, Lampronti I, Bianchi N, Mancini I, Marzaro G, dall'Acqua F, Guiotto A, Gambari R. Development of a novel furocoumarin derivative inhibiting NF-κ B dependent biological functions: design, synthesis and biological effects. Eur J Med Chem. 2011 Oct;46(10):4870-7. doi: 10.1016/j.ejmech.2011.07.032. PubMed PMID: 21864947.
- Gambari R, Fabbri E, Borgatti M, Lampronti I, Finotti A, Brognara E, Bianchi N, Manicardi A, Marchelli R, Corradini R. Targeting microRNAs involved in human diseases: a novel approach for modification of gene expression and drug development. Biochem Pharmacol. 2011 Nov 15;82(10):1416-29. doi: 10.1016/j.bcp.2011.08.007. Review. PubMed PMID: 21864506.
- Borgatti M, Mancini I, Bianchi N, Guerrini A, Lampronti I, Rossi D, Sacchetti G, Gambari R. Bergamot (Citrus bergamia Risso) fruit extracts and identified components alter expression of interleukin 8 gene in cystic fibrosis bronchial epithelial cell lines. BMC Biochem. 2011 Apr 15;12:15. doi: 10.1186/1471-2091-12-15. PubMed PMID: 21496221; PubMed Central PMCID: PMC3095539.
- Mazzitelli S, Borgatti M, Breveglieri G, Gambari R, Nastruzzi C. Encapsulation of eukaryotic cells in alginate microparticles: cell signaling by TNF-alpha through capsular structure of cystic fibrosis cells. J Cell Commun Signal. 2011 Jun;5(2):157-65. doi: 10.1007/s12079-010-0105-z. PubMed PMID: 21484183; PubMed Central PMCID: PMC3088797.
- Tamanini A, Borgatti M, Finotti A, Piccagli L, Bezzerri V, Favia M, Guerra L, Lampronti I, Bianchi N, Dall'Acqua F, Vedaldi D, Salvador A, Fabbri E, Mancini I, Nicolis E, Casavola V, Cabrini G, Gambari R. Trimethylangelicin reduces IL-8 transcription and potentiates CFTR function. Am J Physiol Lung Cell Mol Physiol. 2011 Mar;300(3):L380-90. doi: 10.1152/ajplung.00129.2010. PubMed PMID: 21148790.
- Piccagli L, Borgatti M, Nicolis E, Bianchi N, Mancini I, Lampronti I, Vevaldi D, Dall'Acqua F, Cabrini G, Gambari R. Virtual screening against nuclear factor κB (NF-κB) of a focus library: Identification of bioactive furocoumarin derivatives inhibiting NF-κ B dependent biological functions involved in cystic fibrosis. Bioorg Med Chem. 2010 Dec 1;18(23):8341-9. doi: 10.1016/j.bmc.2010.09.063. PubMed PMID: 20980154.
- Cabrini G, Bezzerri V, Mancini I, Nicolis E, Dechecchi MC, Tamanini A, Lampronti I, Piccagli L, Bianchi N, Borgatti M, Gambari R. Targeting transcription factor activity as a strategy to inhibit pro-inflammatory genes involved in cystic fibrosis: decoy oligonucleotides and low-molecular weight compounds. Curr Med Chem. 2010;17(35):4392-404. Review. PubMed PMID: 20939807.
- Borgatti M, Mazzitelli S, Breveglieri G, Gambari R, Nastruzzi C. Induction by TNF-α of IL-6 and IL-8 in cystic fibrosis bronchial IB3-1 epithelial cells encapsulated in alginate microbeads. J Biomed Biotechnol. 2010;2010. pii: 907964. doi: 10.1155/2010/907964. PubMed PMID: 20936184; PubMed Central PMCID: PMC2946646.
- Salvador A, Dall'Acqua S, Sardo MS, Caffieri S, Vedaldi D, Dall'Acqua F, Borgatti M, Zuccato C, Bianchi N, Gambari R. Erythroid induction of chronic myelogenous leukemia K562 cells following treatment with a photoproduct derived from the UV-A irradiation of 5-methoxypsoralen. ChemMedChem. 2010 Sep 3;5(9):1506-12. doi: 10.1002/cmdc.201000204. PubMed PMID: 20645383.
- Pensato S, Saviano M, Bianchi N, Borgatti M, Fabbri E, Gambari R, Romanelli A. gamma-Hydroxymethyl PNAs: Synthesis, interaction with DNA and inhibition of protein/DNA interactions. Bioorg Chem. 2010 Oct;38(5):196-201. doi: 10.1016/j.bioorg.2010.06.002. PubMed PMID: 20643471.
- Destro F, Borgatti M, Iafelice B, Gavioli R, Braun T, Bauer J, Böttcher L, Jung E, Bocchi M, Guerrieri R, Gambari R. Effects of biomaterials for Lab-on-a-chip production on cell growth and expression of differentiated functions of leukemic cell lines. J Mater Sci Mater Med. 2010 Sep;21(9): 2653-64. doi: 10.1007/s10856-010-4125-2. PubMed PMID: 20625835.
- Gambari R, Borgatti M, Bezzerri V, Nicolis E, Lampronti I, Dechecchi MC, Mancini I, Tamanini A, Cabrini G. Decoy oligodeoxyribonucleotides and peptide nucleic acids-DNA chimeras targeting nuclear factor kappa-B: inhibition of IL-8 gene expression in cystic fibrosis cells infected with Pseudomonas aeruginosa. Biochem Pharmacol. 2010 Dec 15;80(12):1887-94. doi: 10.1016/j.bcp. 2010.06.047. Review. PubMed PMID: 20615393.
- Ruimi N, Rwashdeh H, Wasser S, Konkimalla B, Efferth T, Borgatti M, Gambari R, Mahajna J. Daedalea gibbosa substances inhibit LPS-induced expression of iNOS by suppression of NF-kappaB and MAPK activities in RAW 264.7 macrophage cells. Int J Mol Med. 2010 Mar;25(3):421-32. PubMed PMID: 20127048.
- Mangolini A, Bogo M, Durante C, Borgatti M, Gambari R, Harris PC, Rizzuto R, Pinton P, Aguiari G, del Senno L. NF-kappaB activation is required for apoptosis in fibrocystin/polyductin-depleted kidney epithelial cells. Apoptosis. 2010 Jan;15(1):94-104. doi: 10.1007/s10495-009-0426-7. PubMed PMID: 19943112.
- Mazzuferi M, Bovolenta R, Bocchi M, Braun T, Bauer J, Jung E, Iafelice B, Guerrieri R, Destro F, Borgatti M, Bianchi N, Simonato M, Gambari R. The biocompatibility of materials used in printed circuit board technologies with respect to primary neuronal and K562 cells. Biomaterials. 2010 Feb;31(6):1045-54. doi: 10.1016/j.biomaterials.2009.10.025. PubMed PMID: 19878988.
- Salvatori F, Breveglieri G, Zuccato C, Finotti A, Bianchi N, Borgatti M, Feriotto G, Destro F, Canella A, Brognara E, Lampronti I, Breda L, Rivella S, Gambari R. Production of beta-globin and adult hemoglobin following G418 treatment of erythroid precursor cells from homozygous beta(0)39 Thalassemia patients. Am J Hematol. 2009 Nov;84(11):720-8. doi: 10.1002/ajh.21539. PubMed PMID: 19810011; PubMed Central PMCID: PMC3572903.
- Piccagli L, Fabbri E, Borgatti M, Bianchi N, Bezzerri V, Mancini I, Nicolis E, Dechecchi CM, Lampronti I, Cabrini G, Gambari R. Virtual screening against p50 NF-kappaB transcription factor for the identification of inhibitors of the NF-kappaB-DNA interaction and expression of NF-kappaB upregulated genes. ChemMedChem. 2009 Dec;4(12):2024-33. doi: 10.1002/cmdc.200900362. PubMed PMID: 19806632.
- Lampronti I, Bianchi N, Zuccato C, Dall'acqua F, Vedaldi D, Viola G, Potenza R, Chiavilli F, Breveglieri G, Borgatti M, Finotti A, Feriotto G, Salvatori F, Gambari R. Increase in gamma-globin mRNA content in human erythroid cells treated with angelicin analogs. Int J Hematol. 2009 Oct;90(3):318-27. doi: 10.1007/s12185-009-0422-2. PubMed PMID: 19777196.
- Rizzo R, Dal Canto MB, Stignani M, Fadini R, Fumagalli D, Renzini MM, Borgatti M, Gambari R, Baricordi OR. Production of sHLA-G molecules by in vitro matured cumulus-oocyte complex. Int J Mol Med. 2009 Oct;24(4):523-30. PubMed PMID: 19724893.
- Piva R, Penolazzi L, Borgatti M, Lampronti I, Lambertini E, Torreggiani E, Gambari R. Apoptosis of human primary osteoclasts treated with molecules targeting nuclear factor-kappaB. Ann N Y Acad Sci. 2009 Aug;1171:448-56. doi: 10.1111/j.1749-6632.2009.04906.x. Review. PubMed PMID: 19723088.
- Viola G, Salvador A, Vedaldi D, Dall'Acqua F, Bianchi N, Zuccato C, Borgatti M, Lampronti I, Gambari R. Differentiation and apoptosis in UVA-irradiated cells treated with furocoumarin derivatives. Ann N Y Acad Sci. 2009 Aug; 1171:334-44. doi: 10.1111/j.1749-6632.2009.04894.x. Review. PubMed PMID: 19723073.
- Nicolis E, Lampronti I, Dechecchi MC, Borgatti M, Tamanini A, Bezzerri V, Bianchi N, Mazzon M, Mancini I, Giri MG, Rizzotti P, Gambari R, Cabrini G. Modulation of expression of IL-8 gene in bronchial epithelial cells by 5-methoxypsoralen. Int Immunopharmacol. 2009 Nov;9(12):1411-22. doi: 10.1016/j.intimp.2009.08.013. PubMed PMID: 19720161.
- Bianchi N, Zuccato C, Lampronti I, Borgatti M, Gambari R. Expression of miR-210 during erythroid differentiation and induction of gamma-globin gene expression. BMB Rep. 2009 Aug 31;42(8):493-9. PubMed PMID: 19712585.
- Guerrini A, Lampronti I, Bianchi N, Zuccato C, Breveglieri G, Salvatori F, Mancini I, Rossi D, Potenza R, Chiavilli F, Sacchetti G, Gambari R, Borgatti M. Bergamot (Citrus bergamia Risso) fruit extracts as γ -globin gene expression inducers: phytochemical and functional perspectives. J Agric Food Chem. 2009 May 27;57(10):4103-11. doi: 10.1021/jf803489p. PubMed PMID: 19371028.
- Salvatori F, Cantale V, Breveglieri G, Zuccato C, Finotti A, Bianchi N, Borgatti M, Feriotto G, Destro F, Canella A, Breda L, Rivella S, Gambari R. Development of K562 cell clones expressing beta-globin mRNA carrying the beta039 thalassaemia mutation for the screening of correctors of stop-codon mutations. Biotechnol Appl Biochem. 2009 Jul 9;54(1):41-52. doi: 10.1042/BA20080266. PubMed PMID: 19216718; PubMed Central PMCID: PMC3582994.
- Borgatti M, Finotti A, Falzarano S, Selvatici R. Structural characterization of promoter sequences of the gene coding human PKI55 protein, a protein kinase C inhibitor. Biochimie. 2009 Apr;91(4):466-74. doi: 10.1016/j.biochi. 2008.11.007. PubMed PMID: 19095038.
- Borgatti M, Rizzo R, Canto MB, Fumagalli D, Renzini MM, Fadini R, Stignani M, Baricordi OR, Gambari R. Release of sICAM-1 in oocytes and in vitro fertilized human embryos. PLoS One. 2008;3(12):e3970. doi: 10.1371/journal.pone. 0003970. PubMed PMID: 19092999; PubMed Central PMCID: PMC2599884.
- Bianchi N, Borgatti M, Fibach E, Prus E, Zuccato C, Breveglieri G, Baraldi PG, Romagnoli R, Gambari R. Bis-epoxyethyl derivatives of distamycin A modified on the amidino moiety: induction of production of fetal hemoglobin in human erythroid precursor cells. Int J Mol Med. 2009 Jan;23(1):105-11. PubMed PMID: 19082513.
- Accetta A, Corradini R, Sforza S, Tedeschi T, Brognara E, Borgatti M, Gambari R, Marchelli R. New uracil dimers showing erythroid differentiation inducing activities. J Med Chem. 2009 Jan 8;52(1):87-94. doi: 10.1021/jm800982q. PubMed PMID: 19072686.
- Penolazzi L, Lampronti I, Borgatti M, Khan MT, Zennaro M, Piva R, Gambari R. Induction of apoptosis of human primary osteoclasts treated with extracts from the medicinal plant Emblica officinalis. BMC Complement Altern Med. 2008 Oct 30;8:59. doi: 10.1186/1472-6882-8-59. PubMed PMID: 18973662; PubMed Central PMCID: PMC2587459.
- Bianchi N, Zuccato C, Lampronti I, Borgatti M, Gambari R. Fetal Hemoglobin Inducers from the Natural World: A Novel Approach for Identification of Drugs for the Treatment of {beta}-Thalassemia and Sickle-Cell Anemia. Evid Based Complement Alternat Med. 2009 Jun;6(2):141-51. doi: 10.1093/ecam/nem139. PubMed PMID: 18955291; PubMed Central PMCID: PMC2686630.
- Lampronti I, Khan MT, Borgatti M, Bianchi N, Gambari R. Inhibitory Effects of Bangladeshi Medicinal Plant Extracts on Interactions between Transcription Factors and Target DNA Sequences. Evid Based Complement Alternat Med. 2008 Sep;5(3):303-12. doi: 10.1093/ecam/nem042. PubMed PMID: 18830455; PubMed Central PMCID: PMC2529391.
- Dechecchi MC, Nicolis E, Norez C, Bezzerri V, Borgatti M, Mancini I, Rizzotti P, Ribeiro CM, Gambari R, Becq F, Cabrini G. Anti-inflammatory effect of miglustat in bronchial epithelial cells. J Cyst Fibros. 2008 Nov;7(6): 555-65. doi: 10.1016/j.jcf.2008.06.002. PubMed PMID: 18815075.
- Piccagli L, Fabbri E, Borgatti M, Bezzerri V, Mancini I, Nicolis E, Dechecchi MC, Lampronti I, Cabrini G, Gambari R. Docking of molecules identified in bioactive medicinal plants extracts into the p50 NF-kappaB transcription factor: correlation with inhibition of NF-kappaB/DNA interactions and inhibitory effects on IL-8 gene expression. BMC Struct Biol. 2008 Sep 3;8:38. doi: 10.1186/1472-6807-8-38. PubMed PMID: 18768082; PubMed Central PMCID: PMC2543017.
- Nicolis E, Lampronti I, Dechecchi MC, Borgatti M, Tamanini A, Bianchi N, Bezzerri V, Mancini I, Giri MG, Rizzotti P, Gambari R, Cabrini G. Pyrogallol, an active compound from the medicinal plant Emblica officinalis, regulates expression of pro-inflammatory genes in bronchial epithelial cells. Int Immunopharmacol. 2008 Dec 10;8(12):1672-80. doi: 10.1016/j.intimp. 2008.08.001. PubMed PMID: 18760383.
- Viola G, Vedaldi D, Dall'Acqua F, Lampronti I, Bianchi N, Zuccato C, Borgatti M, Gambari R. Furocoumarins photolysis products induce differentiation of human erythroid cells. J Photochem Photobiol B. 2008 Jul 24;92(1):24-8. doi: 10.1016/j.jphotobiol.2008.04.001. PubMed PMID: 18485726.
- Cortesi R, Mischiati C, Borgatti M, Breda L, Romanelli A, Saviano M, Pedone C, Gambari R, Nastruzzi C. Formulations for natural and peptide nucleic acids based on cationic polymeric submicron particles. AAPS J. 2004;6(1):10-21. doi: 10.1208/ps060102. PubMed PMID: 18465254; PubMed Central PMCID: PMC2750937.
- Bezzerri V, Borgatti M, Nicolis E, Lampronti I, Dechecchi MC, Mancini I, Rizzotti P, Gambari R, Cabrini G. Transcription factor oligodeoxynucleotides to NF-kappaB inhibit transcription of IL-8 in bronchial cells. Am J Respir Cell Mol Biol. 2008 Jul;39(1):86-96. doi: 10.1165/rcmb.2007-0176OC. PubMed PMID: 18258920.
- Feriotto G, Salvatori F, Finotti A, Breveglieri G, Venturi M, Zuccato C, Bianchi N, Borgatti M, Lampronti I, Mancini I, Massei F, Favre C, Gambari R. A novel frameshift mutation (+A) at codon 18 of the beta-globin gene associated with high persistence of fetal hemoglobin phenotype and deltabetathalassemia. Acta Haematol. 2008;119(1):28-37. doi: 10.1159/000114204. PubMed PMID: 18230963.
- Borgatti M, Bianchi N, Mancini I, Feriotto G, Gambari R. New trends in non-invasive prenatal diagnosis: applications of dielectrophoresis-based Lab-on-a-chip platforms to the identification and manipulation of rare cells. Int J Mol Med. 2008 Jan;21(1):3-12. Review. PubMed PMID: 18097610.
- Viola G, Vedaldi D, Dall'Acqua F, Fortunato E, Basso G, Bianchi N, Zuccato C, Borgatti M, Lampronti I, Gambari R. Induction of gamma-globin mRNA, erythroid differentiation and apoptosis in UVA-irradiated human erythroid cells in the presence of furocumarin derivatives. Biochem Pharmacol. 2008 Feb 15;75(4): 810-25. PubMed PMID: 18022602.
- Moggio L, Romanelli A, Gambari R, Bianchi N, Borgatti M, Fabbri E, Mancini I, di Blasio B, Pedone C, Messere A. Alternate PNA-DNA chimeras (PNA-DNA)(n): synthesis, binding properties and biological activity. Biopolymers. 2007;88(6):815-22. PubMed PMID: 17918186.
- Borgatti M, Bezzerri V, Mancini I, Nicolis E, Dechecchi MC, Lampronti I, Rizzotti P, Cabrini G, Gambari R. Induction of IL-6 gene expression in a CF bronchial epithelial cell line by Pseudomonas aeruginosa is dependent on transcription factors belonging to the Sp1 superfamily. Biochem Biophys Res Commun. 2007 Jun 15;357(4):977-83. PubMed PMID: 17466942.
- Piva R, Penolazzi L, Zennaro M, Bianchini E, Magri E, Borgatti M, Lampronti I, Lambertini E, Tavanti E, Gambari R. Induction of apoptosis of osteoclasts by targeting transcription factors with decoy molecules. Ann N Y Acad Sci. 2006 Dec;1091:509-16. Review. PubMed PMID: 17341640.
- Dechecchi MC, Nicolis E, Bezzerri V, Vella A, Colombatti M, Assael BM, Mettey Y, Borgatti M, Mancini I, Gambari R, Becq F, Cabrini G. MPB-07 reduces the inflammatory response to Pseudomonas aeruginosa in cystic fibrosis bronchial cells. Am J Respir Cell Mol Biol. 2007 May;36(5):615-24. PubMed PMID: 17197571.
- Zuccato C, Bianchi N, Borgatti M, Lampronti I, Massei F, Favre C, Gambari R. Everolimus is a potent inducer of erythroid differentiation and gammaglobin gene expression in human erythroid cells. Acta Haematol. 2007;117(3):168-76. PubMed PMID: 17148936.
- Messere A, Fabbri E, Borgatti M, Gambari R, Di Blasio B, Pedone C, Romanelli A. Antiproliferative activity of Pt(II) and Pd(II) phosphine complexes with thymine and thymidine. J Inorg Biochem. 2007 Feb;101(2):254-60. PubMed PMID: 17097738.
- Fibach E, Bianchi N, Borgatti M, Zuccato C, Finotti A, Lampronti I, Prus E, Mischiati C, Gambari R. Effects of rapamycin on accumulation of alpha-, beta- and gamma-globin mRNAs in erythroid precursor cells from beta-thalassaemia patients. Eur J Haematol. 2006 Nov;77(5):437-41. PubMed PMID: 16939628.
- Lampronti I, Khan MT, Bianchi N, Ather A, Borgatti M, Vizziello L, Fabbri E, Gambari R. Bangladeshi medicinal plant extracts inhibiting molecular interactions between nuclear factors and target DNA sequences mimicking NF-kappaB binding sites. Med Chem. 2005 Jul;1(4):327-33. PubMed PMID: 16789890.
- Romagnoli R, Baraldi PG, Pavani MG, Tabrizi MA, Preti D, Fruttarolo F, Piccagli L, Jung MK, Hamel E, Borgatti M, Gambari R. Synthesis and biological evaluation of 2-amino-3-(3',4',5'-trimethoxybenzoyl)-5-aryl thiophenes as a new class of potent antitubulin agents. J Med Chem. 2006 Jun 29;49(13):3906-15. PubMed PMID: 16789746.
- Borgatti M, Boyd DD, Lampronti I, Bianchi N, Fabbri E, Saviano M, Romanelli A, Pedone C, Gambari R. Decoy molecules based on PNA-DNA chimeras and Targeting Sp1 transcription factors inhibit the activity of urokinase-type plasminogen activator receptor (uPAR) promoter. Oncol Res. 2005;15(7-8):373-83. PubMed PMID: 16491955.
- Ronchetti D, Impagnatiello F, Guzzetta M, Gasparini L, Borgatti M, Gambari R, Ongini E. Modulation of iNOS expression by a nitric oxide-releasing derivative of the natural antioxidant ferulic acid in activated RAW 264.7 macrophages. Eur J Pharmacol. 2006 Feb 17;532(1-2):162-9. PubMed PMID: 16443213.
- Romagnoli R, Baraldi PG, Tabrizi MA, Bermejo J, Estévez F, Borgatti M, Gambari R. Design, synthesis, and biological evaluation of hybrid molecules containing alpha-methylene-gamma-butyrolactones and alpha-bromoacryloyl moieties. J Med Chem. 2005 Dec 1;48(24):7906-10. PubMed PMID: 16302827.
- Cozzani M, Giovannini I, Naccari R, Penolazzi L, Lambertini E, Borgatti M, Piva R, Gambari R, Siciliani G. Transcription Factor Decoy (TFD) as a novel approach for the control of osteoclastic resorption. Prog Orthod. 2005;6(2):238-47. Review. English, Italian. PubMed PMID: 16276433.
- Borgatti M, Altomare L, Abonnec M, Fabbri E, Manaresi N, Medoro G, Romani A, Tartagni M, Nastruzzi C, Di Croce S, Tosi A, Mancini I, Guerrieri R, Gambari R. Dielectrophoresis-based 'Lab-on-a-chip' devices for programmable binding of microspheres to target cells. Int J Oncol. 2005 Dec;27(6):1559-66. PubMed PMID: 16273212.
- Romagnoli R, Baraldi PG, Iaconinoto MA, Carrion MD, Tabrizi MA, Gambari R, Borgatti M, Heilmann J. Synthesis and biological activity of alphabromoacryloyl lexitropsin conjugates. Eur J Med Chem. 2005 Nov;40(11):1123-8. PubMed PMID: 16006014.
- Lampronti I, Bianchi N, Borgatti M, Fabbri E, Vizziello L, Khan MT, Ather A, Brezena D, Tahir MM, Gambari R. Effects of vanadium complexes on cell growth of human leukemia cells and protein-DNA interactions. Oncol Rep. 2005 Jul;14(1):9-15. PubMed PMID: 15944761.
- Borgatti M, Altomare L, Baruffa M, Fabbri E, Breveglieri G, Feriotto G, Manaresi N, Medoro G, Romani A, Tartagni M, Gambari R, Guerrieri R. Separation of white blood cells from erythrocytes on a dielectrophoresis (DEP) based 'Lab-on-a-chip' device. Int J Mol Med. 2005 Jun;15(6):913-20. PubMed PMID: 15870893.
- Borgatti M, Finotti A, Romanelli A, Saviano M, Bianchi N, Lampronti I, Lambertini E, Penolazzi L, Nastruzzi C, Mischiati C, Piva R, Pedone C, Gambari R. Peptide nucleic acids (PNA)-DNA chimeras targeting transcription factors as a tool to modify gene expression. Curr Drug Targets. 2004 Nov;5(8):735-44. Review. PubMed PMID: 15578953.
- Mischiati C, Sereni A, Finotti A, Breda L, Cortesi R, Nastruzzi C, Romanelli A, Saviano M, Bianchi N, Pedone C, Borgatti M, Gambari R. Complexation to cationic microspheres of double-stranded peptide nucleic acid-DNA chimeras exhibiting decoy activity. J Biomed Sci. 2004 Sep-Oct;11(5):697-704. PubMed PMID: 15316146.
- Mischiati C, Sereni A, Lampronti I, Bianchi N, Borgatti M, Prus E, Fibach E, Gambari R. Rapamycin-mediated induction of gamma-globin mRNA accumulation in human erythroid cells. Br J Haematol. 2004 Aug;126(4):612-21. PubMed PMID: 15287957.
- Penolazzi L, Borgatti M, Lambertini E, Mischiati C, Finotti A, Romanelli A, Saviano M, Pedone C, Piva R, Gambari R. Peptide nucleic acid-DNA decoy chimeras targeting NF-kappaB transcription factors: Induction of apoptosis in human primary osteoclasts. Int J Mol Med. 2004 Aug;14(2):145-52. PubMed PMID: 15254756.
- Cortesi R, Mischiati C, Borgatti M, Breda L, Romanelli A, Saviano M, Pedone C, Gambari R, Nastruzzi C. Formulations for natural and peptide nucleic acids based on cationic polymeric submicron particles. AAPS PharmSci. 2004 Jan 20;6(1):E2. PubMed PMID: 15198503.
- Mischiati C, Finotti A, Sereni A, Boschetti S, Baraldi PG, Romagnoli R, Feriotto G, Jeang KT, Bianchi N, Borgatti M, Gambari R. Binding of hybrid molecules containing pyrrolo [2,1-c][1,4]benzodiazepine (PBD) and oligopyrrole carriers to the human immunodeficiency type 1 virus TAR-RNA. Biochem Pharmacol. 2004 Feb 1;67(3):401-10. PubMed PMID: 15037192.
- Lambertini E, Piva R, Khan MT, Lampronti I, Bianchi N, Borgatti M, Gambari R. Effects of extracts from Bangladeshi medicinal plants on in vitro proliferation of human breast cancer cell lines and expression of estrogen receptor alpha gene. Int J Oncol. 2004 Feb;24(2):419-23. PubMed PMID: 14719119.
- Tomassetti M, Feriotto G, Giacomini P, Giorda E, Bianchi N, Borgatti M, Finotti A, Mischiati C, Gambari R. Identification of a novel DNase I hypersensitive site within the far upstream region of the human HLA-DRA gene. Int J Mol Med. 2003 Dec;12(6):929-34. PubMed PMID: 14612968.
- Penolazzi L, Lambertini E, Borgatti M, Piva R, Cozzani M, Giovannini I, Naccari R, Siciliani G, Gambari R. Decoy oligodeoxynucleotides targeting NF-kappaB transcription factors: induction of apoptosis in human primary osteoclasts. Biochem Pharmacol. 2003 Oct 1;66(7):1189-98. PubMed PMID: 14505798.
- Lampronti I, Bianchi N, Borgatti M, Fibach E, Prus E, Gambari R. Accumulation of gamma-globin mRNA in human erythroid cells treated with angelicin. Eur J Haematol. 2003 Sep;71(3):189-95. PubMed PMID: 12930320.
- Chiarabelli C, Bianchi N, Borgatti M, Prus E, Fibach E, Gambari R. Induction of gamma-globin gene expression by tallimustine analogs in human erythroid cells. Haematologica. 2003 Jul;88(7):826-7. PubMed PMID: 12857563.
- Lampronti I, Martello D, Bianchi N, Borgatti M, Lambertini E, Piva R, Jabbar S, Choudhuri MS, Khan MT, Gambari R. In vitro antiproliferative effects on human tumor cell lines of extracts from the Bangladeshi medicinal plant Aegle marmelos Correa. Phytomedicine. 2003 May;10(4):300-8. PubMed PMID: 12809360.
- Fibach E, Bianchi N, Borgatti M, Prus E, Gambari R. Mithramycin induces fetal hemoglobin production in normal and thalassemic human erythroid precursor cells. Blood. 2003 Aug 15;102(4):1276-81. PubMed PMID: 12738678.
- Borgatti M, Romanelli A, Saviano M, Pedone C, Lampronti I, Breda L, Nastruzzi C, Bianchi N, Mischiati C, Gambari R. Resistance of decoy PNA-DNA chimeras to enzymatic degradation in cellular extracts and serum. Oncol Res. 2003;13(5):279-87. PubMed PMID: 12688679.
- Altomare L, Borgatti M, Medoro G, Manaresi N, Tartagni M, Guerrieri R, Gambari R. Levitation and movement of human tumor cells using a printed circuit board device based on software-controlled dielectrophoresis. Biotechnol Bioeng. 2003 May 20;82(4):474-9. PubMed PMID: 12632404.
- Gambari R, Borgatti M, Altomare L, Manaresi N, Medoro G, Romani A, Tartagni M, Guerrieri R. Applications to cancer research of "lab-on-a-chip" devices based on dielectrophoresis (DEP). Technol Cancer Res Treat. 2003 Feb;2(1):31-40. PubMed PMID: 12625752.
- Borgatti M, Lampronti I, Romanelli A, Pedone C, Saviano M, Bianchi N, Mischiati C, Gambari R. Transcription factor decoy molecules based on a peptide nucleic acid (PNA)-DNA chimera mimicking Sp1 binding sites. J Biol Chem. 2003 Feb 28;278(9):7500-9. PubMed PMID: 12446679.
- Borgatti M, Breda L, Cortesi R, Nastruzzi C, Romanelli A, Saviano M, Bianchi N, Mischiati C, Pedone C, Gambari R. Cationic liposomes as delivery systems for double-stranded PNA-DNA chimeras exhibiting decoy activity against NFkappaB transcription factors. Biochem Pharmacol. 2002 Aug 15;64(4):609-16. PubMed PMID: 12167479.
- Mischiati C, Borgatti M, Feriotto G, Rutigliano C, Breda L, Bianchi N, Gambari R. Inhibition of HIV-1 LTR-driven in vitro transcription by molecular hybrids based on peptide nucleic acids mimicking the NF-kappaB binding site. Int J Mol Med. 2002 Jun;9(6):633-9. PubMed PMID: 12011981.
- Feriotto G, Borgatti M, Mischiati C, Bianchi N, Gambari R. Biosensor technology and surface plasmon resonance for real-time detection of genetically modified Roundup Ready soybean gene sequences. J Agric Food Chem. 2002 Feb 27;50(5):955-62. PubMed PMID: 11853464.
- Catelani G, D'Andrea F, Mastrorilli E, Bianchi N, Chiarabelli C, Borgatti M, Martello D, Gambari R. Preparation and evaluation of the in vitro erythroid differentiation induction properties of some esters of methyl 3,4-O-isopropylidene-beta-D-galactopyranoside and 2,3-O-isopropylidene-D-mannofuranose. Bioorg Med Chem. 2002 Feb;10(2): 347-53. PubMed PMID: 11741783.
- Romanelli A, Pedone C, Saviano M, Bianchi N, Borgatti M, Mischiati C, Gambari R. Molecular interactions with nuclear factor kappaB (NF-kappaB) transcription factors of a PNA-DNA chimera mimicking NF-kappaB binding sites. Eur J Biochem. 2001 Dec;268(23):6066-75. PubMed PMID: 11733000.
- Mischiati C, Jeang KT, Feriotto G, Breda L, Borgatti M, Bianchi N, Gambari R. Aromatic polyamidines inhibiting the Tat-induced HIV-1 transcription recognize structured TAR-RNA. Antisense Nucleic Acid Drug Dev. 2001 Aug;11(4):209-17. PubMed PMID: 11572598.
- Bianchi N, Chiarabelli C, Borgatti M, Mischiati C, Fibach E, Gambari R. Accumulation of gamma-globin mRNA and induction of erythroid differentiation after treatment of human leukaemic K562 cells with tallimustine. Br J Haematol. 2001 Jun;113(4):951-61. PubMed PMID: 11442489.
- Saviano M, Romanelli A, Bucci E, Pedone C, Mischiati C, Bianchi N, Feriotto G, Borgatti M, Gambari R. Computational procedures to explain the different biological activity of DNA/DNA, DNA/PNA and PNA/PNA hybrid molecules mimicking NF-kappaB binding sites. J Biomol Struct Dyn. 2000 Dec;18(3):353-62. PubMed PMID: 11149512.
- Mischiati C, Feriotto G, Borgatti M, Giacomini P, Gambari R. Characterization of a major histocompatibility complex class II X-boxbinding protein enhancing tat-induced transcription directed by the human immunodeficiency virus type 1 long terminal repeat. J Virol. 2000 Oct;74(19):8989-9001. PubMed PMID: 10982343; PubMed Central PMCID: PMC102095.
- Nastruzzi C, Cortesi R, Esposito E, Gambari R, Borgatti M, Bianchi N, Feriotto G, Mischiati C. Liposomes as carriers for DNA-PNA hybrids. J Control Release. 2000 Aug 10;68(2):237-49. PubMed PMID: 10925132.
- Mischiati C, Borgatti M, Bianchi N, Rutigliano C, Tomassetti M, Feriotto G, Gambari R. Interaction of the human NF-kappaB p52 transcription factor with DNA-PNA hybrids mimicking the NF-kappaB binding sites of the human immunodeficiency virus type 1 promoter. J Biol Chem. 1999 Nov 12;274(46):33114-22. PubMed PMID: 10551882.