PhD in Biomedical Sciences and Biotechnology

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CURRICULUM VITAE PEGGY CARLA RAFFAELLA MARCONI

Place of Birth : Caracas, Venezuela

Date of Birth : November 04,1966

Citizenship: Italian

Present position and title: Associate Professor, Ph.D.

Associate Professor in Microbiology
Department of Chemical and Pharmaceutical Sciences (DipSCF)
University of Ferrara
Via Fossato di Mortara 64/A, 44121 Ferrara, Italy
Phone number: +39-0532-455381
e-mail: mcy@unife.it

Language skills: Spanish, Italian, English, French.

EDUCATION
1985/1990 University of Bologna, Italy; BS, , Biological Sciences 110/110 full marks cum laude

1990/1994 University of Ferrara, Italy; Ph.D student, Biothecnologies

1993/1994 University of Pittsburgh, Ph.D fellow, Virology and Molecular Biology

1994 Doctoral Degree Ph.D

CAREER/EMPLOYMENT and RESEARCH EXPERIENCES
1987-1990 B.S. Training in Clinical Immunology. University of Bologna, Italy

1990-1993 Ph.D Student. University of Ferrara, Italy. Research activity. Inhibition of HIV-1 replication by tat transdominant negative mutants using retroviral-vector

1993-1994 PhD Fellow. University of Pittsburgh, School of Medicine. Pittsburgh Pa (USA). Research activity. Development of replication-defective Herpes simplex virus vectors (HSV-1)

1994-1998 Research Associate. University of Pittsburgh, School of Medicine. Pittsburgh Pa (USA). Research activity. Development of replication-defective Herpes simplex virus vectors (HSV-1) for gene transfer in vivo and their application in animal models

1998-2000 Staff Scientist, Project Leader, HSR- TIGET, Istituto Scientifico San Raffaele, Milan, Italy. Research activity. Molecular analysis of behavior and neurological diseases by gene transfer into neurons with Herpes simplex vector.

2000-october 2014 University Researcher (Assistant Professor). University of Ferrara. Research activity. Use of HSV-1 vectors for gene transfer in vivo. Gene therapy approaches. Teaching duties on Microbiology and Viral Gene Therapy

2014- present Professor Associate. University of Ferrara. Research activity on gene terapy, vaccines and basic research on HSV and neurodegeneration. Teaching duties on Microbiology. Applied Microbiology and Viral Gene Therapy

KEY QUALIFICATIONS:

1994 – 1998 Reasearch Associate. University of Pittsburgh, School of Medicine. Pittsburgh Pa (USA).

1998 – 2000 Staff Scientist, Project Leader, HSR- TIGET, Istituto Scientifico San Raffaele, Milan

2000 – October 2014 Assistant Professor. University of Ferrara,

October 2014 – present Associate Professor. University of Ferrara,

2000 – 2012 Member of the Doctorate Committee in Pharmacology and Molecular Oncology, University of Ferrara;

2012 - present Member of the Doctorate Committee in

2000 – present Teaching duties on Microbiology and Applied Microbiology, on Microbiology and Vaccinology in 2nd and 3rd year undergraduate programs into the Pharmacy School and Gene Therapy and Advanced cellular techniques into the Biotechnology degree curriculum and in master program at the University of Ferrara.

PROFESSIONAL SOCIETIES
Membership of professional bodies: SIV (Società Italiana di Virologia: Italian Society of Virology), SIM (Società Italiana di Microbiologia: Italian Society of Microbiology), SIMIF (Società Italiana di Microbiologia Farmaceutica: Italian Society of Pharmaceutilcal Microbiology)

Evaluator 4-7 December 2001 Brussels Belgium. Invited as expert evaluator for proposal evaluation in the Key Action “Control of Infectious Diseases” Programme: QUALITY OF LIFE AND MANAGEMENT OF LIVING RESOURCES – HEALTH RESEARCH. EUROPEAN COMMISSION, Brussels

Evaluator 3-5 June 2004 Segovia – Spain. Invited as “independent expert” evaluator for Mid-term Review of QLK2-2002-01867 “Increasing the Potency of Vaccinia MVA Vaccines” Programma: QUALITY OF LIFE AND MANAGEMENT OF LIVING RESOURCES – HEALTH RESEARCH. EUROPEAN COMMISSION

Evaluator for PRIN proposals/ 2010-2011

She participated to many national and international congresses on Microbiology, Gene Therapy, Vector Development, Cancer Therapy, Vaccines, contributing with talks or posters.

She was involved in an international program for the Theoretical course: Fundamental concepts of HSV-1 infection” and practical course on “Production, titration and evaluation of recombinant vectors by homologous recombination in mammalian cells”; Institut Pasteur de Montevideo, Montevideo, Uruguay, 2008

RESEARCH EXPERIENCES

Since 1987 she is engaged in basic and applied research, she has particular skills in molecular and cellular biology techniques, basic and applied virology and basic immunology. Main research fields in these years: clinical immunology; use of retroviral vectors expressing Tat mutant for HIV-1 gene therapy; development of replication-defective Herpes simplex vectors (HSV-1, HSV-2) for gene transfer in vivo and their application in animal models, both as gene therapy and vaccination vehicles, and analysis of behavior and neurological diseases by gene transfer into neurons with HSV-1 vectors; development of challenge models, based on wild-type Herpes simplex viruses (HSV-1 and HSV-2) engineered to express HIV-1 vaccine genes, for efficacy studies of the vaccine candidates in the murine system.

TEACHING EXPERIENCES

AA 2000-2001

· Applied Microbiology, CTF, Faculty of Pharmacy, University of Ferrara.

AA 2001-2002

· Applied Microbiology, CTF, Faculty of Pharmacy, University of Ferrara.

AA 2002/03

· Theoretical and practical classes in the integrate course of Immunology and Cellular Techniques, Faculty of Pharmacy, University of Ferrara.

· Applied Microbiology, CTF, Faculty of Pharmacy, University of Ferrara

AA 2003/2004

· Microbiology integrated course of Microbiology and Biochemistry, STP, Faculty of Pharmacy, University of Ferrara

· Applied Microbiology, CTF, Faculty of Pharmacy, University of Ferrara.