PhD in Biomedical Sciences and Biotechnology

 

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CURRICULUM VITAE MONICA BORGATTI


Date of birth: 29/10/1973

Nationality: Italian

 

EDUCATION AND TRAINING

2007: Training at the University of Minnesota, Stem Cell Institute, Minneapolis, USA.

2004: Ph.D. in Biotechnology, Department of Biochemistry and Molecular Biology, University of Ferrara, Italy.

1999: Chemical and Pharmaceutical Technologies Degree, University of Ferrara, Italy (magna cum laude).

 

POSITIONS

2015-present: Associate Professor of Biochemistry BIO/10, Department of Life Sciences and Biotechnology, University of Ferrara, Italy.

2011-2015: Assistant Professor of Biochemistry BIO/10, Department of Life Sciences and Biotechnology, University of Ferrara, Italy.

2004-2011: Post Doc, Department of Biochemistry and Molecular Biology, University of Ferrara, Italy.

 

TEACHING COURSES (University of Ferrara)

2015-present: Biochemical and Recombinant DNA technologies (Cellular and biochemical technologies)

2015-present: Environmental Biochemistry

2014: Cellular and Biomolecular Therapies

2013: Stem Cells in Regenerative Medicine

2005-2011: Structural Biochemistry

 

SUPERVISION OF GRADUATE STUDENTS AND POSTDOCTORAL FELLOWS

2000-2016

Number of Postdocs: 10

Number of PhD: 8

Number of Master Students: 17

Department of Life Sciences and Biotechnology, Ferrara University, Italy

Department of Biochemistry and Molecular Biology, Ferrara University, Italy

Biotechnology Center, Ferrara, Italy

 

FUNDING

2012: Coordinator, #01/2012 FFC “The read-through approach for the treatment of cystic fibrosis caused by premature termination codons” (Italian Cystic Fibrosis Research Foundation) (2 years, 80.000 euros).

2011: Principal Investigator, 098/GR-2009-1596647 “Development of non-invasive strategies for prenatal diagnosis of rare diseases based on surface plasmon resonance (SPR)-imaging, peptide nucleic acids probes and PCR-free hybridization” (Young Investigators-Italian Ministry of Health) (4 years, 376.358 euros).

2011: Principal Investigator, “Chronic Obstructive Pulmonary Disease (COPD) in smokers: identification of pro-inflammatory markers and molecules with anti-inflammatory activity” (Chiesi Foundation) (3 years, 60.000 euros).

2010: Coordinator, #02/2010 FFC “Novel cellular model system and therapeutic molecules for the development of a read-through approach for CF caused by stop codon mutations of the CFTR gene” (Italian Cystic Fibrosis Research Foundation) (1 year, 40.000 euros).

2006: Principal Investigator, “Citrus plants as sources of bioactive molecules with pharmaceutical and biomedical applications” (Young researchers-Ferrara University) (1 year, 6000 euros).

2000: Principal Investigator, “Peptide Nucleic Acids (PNA) for the identification of genetically modified organisms (GMO) using advanced technologies” (Young researchers-Ferrara University) (1 year, 2065 euros).

 

RESEARCH INTERESTS

-Peptide nucleic acids as tool to modify gene expression and for the diagnosis of genetic diseases using SPR technologies.

-Biological and diagnostic applications of dielectrophoresis (DEP) based Lab-on-a-chip devices to diagnosis and drug research and development.

-Identification of novel compounds as inducers of erythroid differentiation for β-thalassemia.

-Analysis of anti-inflammatory molecules for cystic fibrosis and COPD diseases.

-Read-through strategy for the treatments of genetic rare diseases caused by nonsense mutations.

PUBLICATIONS (updated January, 2017, Scopus Source)

149 publications (h-index 31, Total citations 2656) including 119 articles in peer-reviewed International Journals, 21 reviews, 7 conference papers, 1 book chapter, 1 Letter

 

PATENTS

Bianchi N, Borgatti M, Gambari R, Lampronti I (2009). Use of angelicin and of its structural analogues for the treatment of thalassemia. United States Patent 7,572,827, Università degli Studi di Ferrara; Associazione Veneta per la Lotta alla Talassemia.

 

AWARDS AND HONORS

2003: Interuniversity Consortium for Biotechnology (CIB) Young Researcher prize

 

PROFESSIONAL SERVICES

-Member of the Medical Sciences and Biotechnology PhD, University of Ferrara, Italy.

-Invited reviewer for Biomaterials, eCAM, Journal of Ethnopharmacology, Nutrition Research, Pharmaceutical Biology.

-Member of the Editorial Board of Evidence-Based Complementary and Alternative Medicine.

 

MAJOR COLLABORATIONS (Topic)

-Prof. Timor Baasov, Technion-Israel Institute of Technology, s, Haifa, Israel. (Read-through derivates)

-Prof. Eitan Fibach, Hadassah Medical Center, Jerusalem, Israel. (Cell cultures as thalassemia models)

-Prof. Roberto Guerrieri, Bologna University, Italy. (Lab-on-a-chip)

-Dr. Giulio Cabrini, University-Hospital Verona, Italy. (Cystic fibrosis)

-Dr. Nicola Altamura, CNR, Bari, Italy. (Yeast models for read-through activity)

-Prof. Adriana Chilin, Department of Pharmaceutical and Pharmacological Sciences, University of Padoa, Italy. (Psoralen derivates for thalassemia)

-Prof. Roberto Corradini,University of Parma, Italy. (PNA analogues)


Researcher unique identifiers: 0000-0001-8470-2496 (ORCID ID); G-2611-2015 (Research ID), 7003682206 (SCOPUS ID)