PhD in Biomedical Sciences and Biotechnology
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CURRICULUM VITAE ANDRÉS F. MURO
Date and place of birth: Buenos Aires (Argentina), November 15th, 1964 Nationality:Argentinian/Italian
Affiliation and official address: Mouse Molegular Genetics Group, International Centre of Genetic Engineering and Biotechnology (ICGEB), Padriciano, 99, 24149, Trieste, Italy
Telephone: +39-040-3757369 (office) +39-040-3757312 (lab) +39-040-226555 (Fax)
e-mail: muro@icgeb.org
EDUCATION
1982−1988: Master of Sciences in Molecular Biology, University of Buenos Aires, Argentina, School of Sciences.
1988−1992: Doctor in Biology (PhD., Biology), University of Buenos Aires, Argentina, School of Sciences.
CAREER/EMPLOYMENT
1988-1992: Graduate Student Fellowship, Consejo Nacional de Investigaciones Científicas y Técnicas (CONICET), Argentina, to work at the INGEBI, Buenos Aires, Argentina.
1992-1994: ICGEB-UNIDO post-doctoral fellowship, Molecular Pathology Group of the ICGEB, Trieste, Italy.
1995-2004: Staff Scientist Position at the Molecular Pathology Group of the ICGEB, Trieste, Italy.
2005-present: Group Leader of the Mouse Molecule Genetics Group at the International Centre of Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy.
RESEARCH EXPERIENCES
1987-1988: Undergraduate student at the School of Sciences, University of Buenos Aires, Argentina, Dept of Biological Chemistry (Prof. M.L. Cantore and S. Passeron)
1988-1992: PhD student at the Institute for Investigations in Genetic Engineering and Molecular Biology (INGEBI), CONICET, Buenos Aires, Argentina (Prof. Alberto R. Kornblihtt)
1992-2004: Post-doc at the International Centre of Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy
2005-present: Group Leader of the Mouse Molecule Genetics Group at the International Centre of Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy
PROFESSIONAL SOCIETIES
2014-Present: Member of the American Society of Gene and Cell Therapy (ASGCT, USA)
2016-present: Member of the European Society of Gene and Cell Therapy (ESGCT)
TEACHING EXPERIENCES
1989: Teaching Instructor at the Institute of Genetic Engineering and Molecular Biology, INGEBI, Buenos Aires, Argentine.
1990-1992 : Teaching Instructor of the Department of Molecular Genetics and Biotechnology, School of Sciences, University of Buenos Aires, Argentine.
1990-1992 : Chief Teaching Instructor of the post-grade course of Genetic Engineer, given by the Institute of Genetic Engineering and Molecular Biology, INGEBI and the University of Buenos Aires, Argentine.
1995 : Invited Professor at Campomar Institute and the University of Buenos Aires, Argentine.
2005-present: Member of the PhD program board of the International Centre of Genetic Engineering and Biotechnology (ICGEB), Trieste, Italy
GRANTS
2008-2012: Principal Investigator Friuli Venezia Giulia Regional Grant, Italy, with a project aimed at the development and characterization of mouse models of human diseases. Co-PIs: C. Tiribelli (Fondazione Italiana Fegato, Trieste), L. De Marco (CRO-IRCCS, Aviano), Prof. L. Cattin (Cattinara Hospital, Trieste)
2008-2012: Collaborator, NIH RO1, USA, with a project focused on the role of fibronectin isoforms in lung fibrosis (PI: Dr. E. White, Michigan, USA)
2010-2014: Principal Investigator Telethon, Italy, focused on the characterization of a novel mouse model of the Crigler-Najjar syndrome, and in the development of therapeutic approaches. Co-PIs: C. Tiribelli (Fondazione Italiana Fegato, Trieste), Prof. G. Tell (Udine University), Prof. S. Gustincich (SISSA, Trieste), Dr. L. Zentilin (ICGEB, Trieste)
2012-2014: Principal Investigator AXA Research Fund, France, to study mechanisms of bilirubin neurotoxicity in neonatal jaundice
2012-2014: Principal Investigator Beneficentia Stiftung, Vaduz, Lichtenstein, to study mechanisms of bilirubin neurotoxicity in neonatal jaundice and to develop potential therapeutic approaches
2013-2015: Principal Investigator Fondazione Intesa San Paolo, Italy, to study the role of alternative polyadenylation of genes associated to Parkinson’s disease
2015-2017: Principal Investigator Beneficentia Stiftung, Vaduz, Lichtenstein, to improve currently used gene therapy approaches
2017-2021: Co-Investigator H2020, EU, to perform a clinical trial in Crigler-Najjar patients, using AAV. PI: Prof. F. Mingozzi, Genethon, France.
PATENTS
2014 – European Patent Office - Treatment of Crigler-Najjar syndrome – Patent No. 14305622.4 - 1410.
2015 – WIPO - Treatment of Hyperbilirubinemia – International Publication Number: WO 2015/162302 A3
Researcher unique identifiers: ORCID: 0000-0002-9628-0494; SCOPUS: 7006690111; Researcher ID: K-3156-2016
